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This may be done because the species is unstable, and cannot be isolated, or simply out of convenience.

Examples of the former include the Corey-Chaykovsky reagent and adrenochrome.

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This would not be in vivo as the donor is sacrificed by experimentation, but it would not be the same as working with the cell alone (a common scenario for in vitro experiments).A fraction of the globular star clusters in our galaxy, as well as those in other massive galaxies, might have formed in situ.The rest might have been accreted from now defunct dwarf galaxies.In the case of observations or photographs of living animals, it means that the organism was observed (and photographed) in the wild, exactly as it was found and exactly where it was found. The organism had not been moved to another (perhaps more convenient) location such as an aquarium.This phrase in situ when used in laboratory science such as cell science can mean something intermediate between in vivo and in vitro.

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